Pediatric high-grade gliomas.

  title={Pediatric high-grade gliomas.},
  author={A. Tirupathi Reddy and John C. Wellons},
  journal={Cancer journal},
  volume={9 2},
High-grade gliomas, including glioblastoma multiforme, anaplastic astrocytoma, and intrinsic pontine, are very difficult to treat in children. Despite aggressive treatment with multimodal therapy, most children with these diseases do not survive. Data from published series support aggressive surgical resection when clinically feasible. Patients who have had aggressive resections tend to have a longer survival than those who have undergone only biopsies or partial resections. Almost all patients… CONTINUE READING


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