Pediatric fatality secondary to EDTA chelation

  title={Pediatric fatality secondary to EDTA chelation},
  author={Arla J. Baxter and Edward P. Krenzelok},
  journal={Clinical Toxicology},
  pages={1083 - 1084}
Background. Chelation therapy has emerged as a popular treatment modality to remove heavy metals that are thought to cause autism. We report a fatality that occurred as a consequence of chelation therapy for autism when the incorrect form of EDTA was administered. Case Report. A five-year-old autistic male was being chelated in a physician's office. While receiving his third treatment he went into cardiac arrest. It was not determined until after the child's death that he had been given edetate… Expand
Commentary on the Abuse of Metal Chelation Therapy in Patients with Autism Spectrum Disorders
  • J. Brent
  • Medicine
  • Journal of Medical Toxicology
  • 2013
Bayesian principles tell us that further testing is likely to yield results within normal reference ranges, but under some circumstances, it is useful to do such testing in order to demonstrate that there is no need for chelation therapy. Expand
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The year 2013 marks a new era in understanding the clinical importance of low-level xenobiotic heavy metal intoxication on human disease, and the efficacy and safety of ethylene diamine tetra aceticExpand
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In treatment of metal poisonings, the top priorities should be prevention of further uptake, decreased absorption from the gastrointestinal tract, and general supportive therapy focusing on theExpand
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It is suggested that in patients with bone marrow failure requiring hemopoietic stem cell transplantation, prior iron chelation may improve survival, and early deferasirox treatment may result in long-term reduction in transfusion requirements. Expand
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Clinical information on the incidence of hypocalcemia associated with specific drug treatment and the underlying pathophysiological mechanisms are reviewed, which can be handled through awareness of this adverse effect induced by certain pharmaceutical compounds on serum calcium concentrations. Expand
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The results of their latest trial, which is focused on patients with type 2 diabetes with nephropathy, are consistent with earlier trials in observing a benefit of calcium disodium EDTA in slowing CKD progression and are reported in this issue of the American Journal of Kidney Diseases. Expand
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  • K. Franz
  • Chemistry, Medicine
  • Current opinion in chemical biology
  • 2013
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Deaths associated with hypocalcemia from chelation therapy--Texas, Pennsylvania, and Oregon, 2003-2005.
  • Medicine
  • MMWR. Morbidity and mortality weekly report
  • 2006
This report describes three deaths associated with chelation-therapy--related hypocalcemia that resulted in cardiac arrest and advises health-care providers and pharmacists to ensure that Na2EDTA is not administered to children during chelation therapy. Expand
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Immunization to protect children and adults from infectious diseases is one of the greatest achievements of public health. Immunization is not without risks, however. It is well established, forExpand
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Clinical Toxicology Downloaded from by on 06/05/11 For personal use only
  • Clinical Toxicology Downloaded from by on 06/05/11 For personal use only