Pediatric autoimmune neuropsychiatric disorders associated with streptococci (PANDAS).

  title={Pediatric autoimmune neuropsychiatric disorders associated with streptococci (PANDAS).},
  author={S. Shulman},
  journal={The Pediatric infectious disease journal},
  volume={18 3},
  • S. Shulman
  • Published 1999
  • Medicine
  • The Pediatric infectious disease journal
  • Current Opinion in Pediatrics 2009, 21:127–130 Purpose of review To review recent developments related to the proposed entity Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococci (so-called ‘PANDAS’). Recent findings The relationship between obsessive–compulsive disorder (OCD) or tics/Tourette’s syndrome in childhood to antecedent group A streptococci (GAS) is unclear. One recent prospective cohort study found that more than 85% of clinical exacerbations in OCD/tic… CONTINUE READING
    27 Citations
    Paediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS).
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    This important study highlights that inaccurate diagnosis and therapy of 'PANDAS' are rampant in the community
      This is a landmark clinical study that found that only a small proportion of 'PANDAS' exacerbations are temporally related to streptococcal infection
        This is a surprising new study that challenges the concept that 'PANDAS' has an autoimmune pathogenesis