Pediatric autoimmune neuropsychiatric disorders associated with streptococci (PANDAS).
@article{Shulman1999PediatricAN, title={Pediatric autoimmune neuropsychiatric disorders associated with streptococci (PANDAS).}, author={S. Shulman}, journal={The Pediatric infectious disease journal}, year={1999}, volume={18 3}, pages={ 281-2 } }
Current Opinion in Pediatrics 2009, 21:127–130 Purpose of review To review recent developments related to the proposed entity Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococci (so-called ‘PANDAS’). Recent findings The relationship between obsessive–compulsive disorder (OCD) or tics/Tourette’s syndrome in childhood to antecedent group A streptococci (GAS) is unclear. One recent prospective cohort study found that more than 85% of clinical exacerbations in OCD/tic… CONTINUE READING
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This important study highlights that inaccurate diagnosis and therapy of 'PANDAS' are rampant in the community
This is a landmark clinical study that found that only a small proportion of 'PANDAS' exacerbations are temporally related to streptococcal infection
This is a surprising new study that challenges the concept that 'PANDAS' has an autoimmune pathogenesis