Pediatric acute lymphoblastic leukemia.
@article{Carroll2003PediatricAL, title={Pediatric acute lymphoblastic leukemia.}, author={W. Carroll and D. Bhojwani and D. Min and E. Raetz and M. Relling and S. Davies and J. Downing and C. Willman and John Calvin Reed}, journal={Hematology. American Society of Hematology. Education Program}, year={2003}, pages={ 102-31 } }
The outcome for children with acute lymphoblastic leukemia (ALL) has improved dramatically with current therapy resulting in an event free survival exceeding 75% for most patients. However significant challenges remain including developing better methods to predict which patients can be cured with less toxic treatment and which ones will benefit from augmented therapy. In addition, 25% of patients fail therapy and novel treatments that are focused on undermining specifically the leukemic… Expand
Supplemental Presentations
Figures, Tables, and Topics from this paper
186 Citations
Advances in Acute Lymphoblastic Leukemia
- Medicine
- American Society for Clinical Laboratory Science
- 2004
- 14
Advances in childhood leukaemia: successful clinical‐trials research leads to individualised therapy
- Medicine
- The Medical journal of Australia
- 2005
- 18
- PDF
References
SHOWING 1-10 OF 258 REFERENCES
Childhood acute lymphoblastic leukaemia--current status and future perspectives.
- Medicine
- The Lancet. Oncology
- 2001
- 256
- PDF
Classification of pediatric acute lymphoblastic leukemia by gene expression profiling.
- Biology, Medicine
- Blood
- 2003
- 587
- PDF
Clinical and biologic features predict poor prognosis in acute lymphoid leukemias in children and adolescents: a Pediatric Oncology Group review.
- Medicine
- Medical and pediatric oncology
- 1986
- 76
Topics in pediatric leukemia--acute lymphoblastic leukemia and late effects in long-term survivors.
- Medicine
- MedGenMed : Medscape general medicine
- 2005
- 4
Outcome of treatment in childhood acute lymphoblastic leukaemia with rearrangements of the 11q23 chromosomal region
- Medicine
- The Lancet
- 2002
- 353
Second neoplasms after acute lymphoblastic leukemia in childhood.
- Medicine
- The New England journal of medicine
- 1991
- 522
INVESTIGATION OF MINIMAL RESIDUAL DISEASE IN CHILDHOOD AND ADULT ACUTE LYMPHOBLASTIC LEUKAEMIA BY MOLECULAR ANALYSIS
- Biology, Medicine
- British journal of haematology
- 1999
- 122
Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia.
- Medicine
- The New England journal of medicine
- 2000
- 557
Incidence of TEL/AML1 fusion in children with relapsed acute lymphoblastic leukemia.
- Biology, Medicine
- Blood
- 1998
- 124