Pediatric Stress: Hormonal Mediators and Human Development

  title={Pediatric Stress: Hormonal Mediators and Human Development},
  author={E. Charmandari and T. Kino and E. Souvatzoglou and G. Chrousos},
  journal={Hormone Research in Paediatrics},
  pages={161 - 179}
  • E. Charmandari, T. Kino, +1 author G. Chrousos
  • Published 2003
  • Medicine
  • Hormone Research in Paediatrics
  • Stress activates the central and peripheral components of the stress system, i.e., the hypothalamic-pituitary-adrenal (HPA) axis and the arousal/sympathetic system. The principal effectors of the stress system are corticotropin-releasing hormone (CRH), arginine vasopressin, the proopiomelanocortin-derived peptides α-melanocyte-stimulating hormone and β-endorphin, the glucocorticoids, and the catecholamines norepinephrine and epinephrine. Appropriate responsiveness of the stress system to… CONTINUE READING
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