Pediatric Fever of Unknown Origin.

@article{Antoon2015PediatricFO,
  title={Pediatric Fever of Unknown Origin.},
  author={James W. Antoon and Nicholas M. Potisek and Jacob A. Lohr},
  journal={Pediatrics in review},
  year={2015},
  volume={36 9},
  pages={
          380-90; quiz 391
        }
}
1. James W. Antoon, MD, PhD* 2. Nicholas M. Potisek, MD† 3. Jacob A. Lohr, MD†† 1. * [] Key MethodDepartment of Pediatrics, Division of General Pediatrics and Adolescent Medicine, University of Illinois at Chicago, Chicago, IL. 2. †Department of Pediatrics, Division of Pediatric Hospital Medicine, Wake Forest School of Medicine, Winston-Salem, NC. 3. ††Department of Pediatrics, Division of General Pediatrics and Adolescent Medicine, University of North Carolina School of Medicine, Chapel Hill, NC. Pediatricians often confuse fever without a source and fever of unknown origin. After…

Figures and Tables from this paper

Fever of Unknown Origin - A Child With an Unusual Case of Juvenile Idiopathic Arthritis
TLDR
A 13-year-old female child who presented to the Pediatric outpatient department of KISTMCTH with a history of fever and arthralgia for three months is presented.
Etiology and Resource Use of Fever of Unknown Origin in Hospitalized Children.
TLDR
The categorical distribution of diagnoses for pediatric FUO has marginally shifted compared to previously reported pediatric studies, and several clinical factors were statistically and significantly different between etiologic categories.
Fever of unknown origin: a retrospective review of pediatric patients from an urban, tertiary care center in Washington, DC
TLDR
The cost associated with hospitalization for FUO may cause clinicians to reconsider inpatient admission for diagnostic work-up of fever, particularly given the evidence demonstrating that many patients are discharged without a diagnosis.
Etiology and clinical characteristics of fever of unknown origin in children: a 15-year experience in a single center
TLDR
Investigation of the etiology, clinical characteristics and prognosis of pediatric FUO in 21 century with more diagnostics available and to analyze the factors for certain disease categories finds undiagnosed portion of F UO have now increased due to development of diagnostic techniques for infectious diseases.
Overview of fever of unknown origin in adult and paediatric patients.
TLDR
This review outlines a case report of an elderly Italian male patient with high fever and migrating arthralgia who underwent many procedures and treatments before a final diagnosis of Adult-onset Still's disease was achieved, highlighting the difficulties in diagnosing certain causes of FUO.
A study of etiology of fever of unknown origin in children aged 2 months to 18 years
TLDR
Enteric fever and tuberculosis were the leading etiologies from infective subgroup of FUO and ALL was the commonest cause from malignancies sub group, found in younger age group as compared to connective tissue diseases.
A Case Report on Fever of Unknown Origin in a School Going Child– An Uncommon Answer in a Common Question
TLDR
A case of FUO is presented in a child which was investigated thoroughly and managed on the line of enteric fever, however, the patient remained febrile and bone marrow culture grew a very uncommon organism- Escherichia coli.
CLINICO-MICROBIOLOGICAL PROFILE OF CULTURE POSITIVE URINARY TRACT INFECTION IN CHILDREN
TLDR
The Culture positive UTI was most common in female and the most common organism were gram negative with good response to empirical antibiotics aminoglycosides, which means in a febrile infant even without any associated symptom exclusion of UTI is recommended.
An 8-Year-Old Male With Fever of Unknown Origin
TLDR
The patient was referred for further evaluation of his prolonged fevers and cough despite treatment with antimicrobial therapy, and azithromycin was added to cover for atypical pneumonia.
UNCOMMON PRESENTATION OF A COMMON DISEASE AS PUO
TLDR
A case of pyrexia of unknown origin in a 35 yr old male presented to us with fever since 2 months which was associated with chills and rigor and his laboratory findings found pancytopenia.
...
...

References

SHOWING 1-10 OF 60 REFERENCES
Periodic fever syndromes.
TLDR
The periodic fever syndromes are now considered to result from primary dysregulation of the innate immune system, and the term autoinflammatory disorders has been advanced to classify these conditions more accurately.
Children with fever of unknown origin in Argentina: an analysis of 113 cases.
TLDR
Children with life-threatening or chronic disorders were older than those with self-limiting conditions andCardiovascular and articular signs and symptoms were more frequent in the former group than the latter group (P = 0.017).
Fever of Unknown Origin: A Diagnostic Approach to This Vexing Problem
TLDR
Although the differential diagnosis of FUO is vast, a thoughtful, focused approach based on information gleaned from a thorough history and physical examination (together with any laboratory or other study results) is preferable to a “shotgun” or “running the list” one.
Fever of unknown origin in adults: Evaluation of 144 cases in a non-university hospital
  • T. Zénone
  • Medicine
    Scandinavian journal of infectious diseases
  • 2006
TLDR
Non-infectious inflammatory diseases emerge as the most prevalent diagnostic category in this series of 144 patients presenting to a non-university hospital with a community-acquired fever of unknown origin.
Clinical spectrum of fever of unknown origin among Indian children
TLDR
Repeated, thorough clinical examination and carefully selected laboratory examinations proved useful in the diagnosis of FUO in Indian children and serology and bone marrow examination were the most useful diagnostic tests.
Fever of Unknown Origin: A Retrospective Study of 95 Children in an Iranian Referral Hospital
TLDR
In patients aged under three years urine culture, bone marrow aspiration and peripheral blood smear proved more helpful in arriving at a final diagnosis of FUO, while in patients aged over three years, history and physical examination also contributed to the final diagnosis.
Diagnostic Approach to Fever of Unknown Origin
TLDR
A basic set of cost-effective tests are proposed that may help identify the etiology of challenging cases when the initial laboratory and radiographic studies fail to reveal an underlying source of FUO.
Prolonged fever of unknown origin in children.
  • H. J. Mcclung
  • Medicine
    American journal of diseases of children
  • 1972
TLDR
All admissions for a ten-year period were reviewed to determine the nature of illnesses which appeared at a referral center in the form of a prolonged fever of unknown origin, and nine children were found to be completely normal physically.
Diagnostic Review : Prolonged Fever of Unknown Origin
TLDR
54 children with prolonged fever of unknown origin are described, with the view toward expediting the diagnostic workup of such children.
...
...