Pediatric Crohn Disease Activity Index: responsive to short-term change.

  title={Pediatric Crohn Disease Activity Index: responsive to short-term change.},
  author={Pavi Singh Kundhal and Jeffrey N Critch and Mary Zachos and Anthony R Otley and Derek Stephens and Anne Marie Griffiths},
  journal={Journal of pediatric gastroenterology and nutrition},
  volume={36 1},
BACKGROUND/AIMS Despite documented feasibility, reliability, and validity, the Pediatric Crohn's Disease Activity Index (PCDAI) has yet to be demonstrated to be sensitive to change in the time frame of acute treatment trials. We evaluated short-term responsiveness and determined the minimal change in PCDAI score associated with a clinically meaningful improvement in disease activity. METHODS Standardized effect size (SES) and standardized response mean (SRM) were calculated as measures of… CONTINUE READING

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