Peculiarities of interaction of monoclonal antibody B2 with polycyclic aromatic hydrocarbons and peptide-mimotope of benzo[a]pyrene

@article{Glushkov2010PeculiaritiesOI,
  title={Peculiarities of interaction of monoclonal antibody B2 with polycyclic aromatic hydrocarbons and peptide-mimotope of benzo[a]pyrene},
  author={Andrey N. Glushkov and S. V. Apal’ko and Anastasiya Yu. Bakulina and Vera A Matveeva and Evgeny A. Khrapov and Mikhail V Kostyanko and V. N. Sil’nikov and Maxim Filipenko},
  journal={Molecular Biology},
  year={2010},
  volume={44},
  pages={616-623}
}
In order to determine the possible mechanisms of interactions of monoclonal antibody B2 with haptens and early synthesized peptide-mimotope of benzo[a]pyrene using the phage display method, amino acid sequences of variable fragments of heavy and light chains are determined and a model of Fab-fragment is constructed. The structure of the antibody active… CONTINUE READING