Peculiarities of Herpes Simplex Virus (HSV) Transcription: An overview

  title={Peculiarities of Herpes Simplex Virus (HSV) Transcription: An overview},
  author={J. Raj{\vc}{\'a}ni and Vojvodov{\'a} Andrea and Re{\vz}uchov{\'a} Ingeborg},
  journal={Virus Genes},
  • J. Rajčáni, Vojvodová Andrea, Režuchová Ingeborg
  • Published 2004
  • Medicine, Biology
  • Virus Genes
  • The herpes simplex virus (HSV) has a 152 kbp dsDNA encoding probably 84 proteins. The approximate number of ORFs is 94, from which seven are doubled. The most probable number of single copy ORFs is 84 after omitting the two latency associated transcripts (LAT)/ORFs and the putative UL27.5 ORF. The high gene number creates a “crowded” genome with several overlapping transcripts. The unique long (UL) segment has at least 10 interposed ORFs, the existence of which was not obvious at first sequence… CONTINUE READING
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