Peculiar artefacts after fixation with glutaraldehyde and osmium tetroxide.

@article{Kuthy1976PeculiarAA,
  title={Peculiar artefacts after fixation with glutaraldehyde and osmium tetroxide.},
  author={E Kuthy and Zsolt Csap{\'o}},
  journal={Journal of microscopy},
  year={1976},
  volume={107 2},
  pages={177-82}
}
Peculiar electron dense granules were observed, in otherwise well preserved structures of the heart muscle and kidney of the rat after a 5-10 min perfusion, a 2 h fixation in the modified Karnovsky solution, followed by a postfixation in Millonig buffer containing 1% OsO4. The granules appeared most frequently on membranes, the surface of the red blood… CONTINUE READING