Pecking order among tumor-specific antigens.

  title={Pecking order among tumor-specific antigens.},
  author={James L. Urban and Carter Van Waes and Hans Schreiber},
  journal={European journal of immunology},
  volume={14 2},
The ultraviolet light-induced fibrosarcoma 1591 is regularly rejected upon transplantation into young syngeneic mice; in rare instances, however, this tumor grows progressively and the tumors that develop are then heritably stable variant progressor tumors (1591-PRO tumors). In this study, we have induced transplantation resistance to 1591-PRO tumors and determined which antigens were recognized by mice that rejected these progressor tumors. We found that cytolytic T cells of such mice… CONTINUE READING
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