Pearson versus Spearman , Kendall ' s Tau Correlation Analysis on Structure-Activity Relationships of Biologic Active Compounds

@inproceedings{BOLBOAC2006PearsonVS,
  title={Pearson versus Spearman , Kendall ' s Tau Correlation Analysis on Structure-Activity Relationships of Biologic Active Compounds},
  author={Sorana-Daniela BOLBOAC and Lorentz J{\"a}ntschi},
  year={2006}
}
A sample of sixty-seven pyrimidine derivatives with inhibitory activity on E. coli dihydrofolate reductase (DHFR) was studied by the use of molecular descriptors family on structure-activity relationships. Starting from the results obtained by applying of MDF-SAR methodology on pyrimidine derivatives and from the assumption that the measured activity (compounds’ inhibitory activity) of a biologically active compounds is a semi-quantitative outcome (can be related with the type of equipment used… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 25 references

Fundamentals of Biostatistics, 4th Edition

  • B. Rosner
  • 1995
Highly Influential
13 Excerpts

An electrophilicity based analysis of toxicity of aromatic compounds towards Tetrahymena pyriformis

  • D R.Roy, R. Parthasarathi, V. Subramanian, P K.Chattaraj
  • QSAR Comb Sci
  • 2006
1 Excerpt

Antiallergic Activity of Substituted Benzamides: Characterization, Estimation and Prediction

  • L. Jäntschi, S. Bolboacă
  • Clujul Medical LXXIX,
  • 2006
1 Excerpt

Antioxidant Efficacy of 3-Indolyl Derivates by Complex Information Integration

  • S. Bolboacă, C. Filip, Ş. Ţigan, L. Jäntschi
  • Clujul Medical LXXIX(2),
  • 2006
1 Excerpt

Modeling of Structure-Toxicity Relationship of Alkyl Metal Compounds by Integration of Complex Structural Information, Terapeutics

  • S. D. Bobloacă, L. Jäntschi
  • Pharmacology and Clinical Toxicology
  • 2006
1 Excerpt

Molecular Descriptors Family on QSAR Modeling of Quinoline-based Compounds Biological Activities, The 10th Electronic Computational Chemistry

  • L. Jäntschi, S. Bolboacă
  • 2006
1 Excerpt

Molecular Descriptors Family on Structure Activity Relationships 5. Antimalarial Activity of 2,4-Diamino-6-Quinazoline Sulfonamide Derivates

  • L. Jäntschi, S. Bolboacă
  • Leonardo Journal of Sciences
  • 2006
1 Excerpt

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