Pearls and pitfalls in experimental in vivo models of headache: conscious behavioral research.

Abstract

BACKGROUND Physiological studies have been determinant for the understanding of migraine pathophysiology and the screening of novel therapeutics. At present, there is no animal model that translates fully the clinical symptoms of migraine, and generally these studies are conducted on anesthetized animals. METHODOLOGY Pain as well as non-painful symptoms… (More)
DOI: 10.1177/0333102412472557

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