Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome

@article{Smith2004PeakPI,
  title={Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome},
  author={Craig J Smith and Hedley C A Emsley and Carole M Gavin and Rachel F. Georgiou and Andy Vail and Elisa M Barberan and Gregory John del Zoppo and John M. Hallenbeck and Nancy J. Rothwell and Stephen John Hopkins and Pippa Tyrrell},
  journal={BMC Neurology},
  year={2004},
  volume={4},
  pages={2 - 2}
}
BACKGROUND Cerebral ischaemia initiates an inflammatory response in the brain and periphery. We assessed the relationship between peak values of plasma interleukin-6 (IL-6) in the first week after ischaemic stroke, with measures of stroke severity and outcome. METHODS Thirty-seven patients with ischaemic stroke were prospectively recruited. Plasma IL-6, and other markers of peripheral inflammation, were measured at pre-determined timepoints in the first week after stroke onset. Primary… CONTINUE READING

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