Peak frequencies of circulating human influenza-specific antibody secreting cells correlate with serum antibody response after immunization.

Abstract

UNLABELLED Upon vaccination, B cells differentiate into antibody secreting cells (ASCs) that migrate via the circulation to tissues. The kinetics of this response and the relationship of circulating ASCs to protective antibody titers have not been completely explored. METHODS Influenza-specific and total-IgG ASCs were enumerated by Elispot and flow… (More)
DOI: 10.1016/j.vaccine.2010.02.088

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