Pe pt id es Application of enzymes for the synthesis of the Cholecystokinin Pentapeptide ( CCK-5 ) A contribution to Green chemistry

@inproceedings{Meng2006PePI,
  title={Pe pt id es Application of enzymes for the synthesis of the Cholecystokinin Pentapeptide ( CCK-5 ) A contribution to Green chemistry},
  author={L Meng and Rajendra Joshi and Heiner Eckstein},
  year={2006}
}
The reversal of the proteolytic cleavage of the peptide bond by proteases leads to the enzymatic peptide synthesis. In contrast to the chemical synthesis enzymes form the peptide bond without the danger of racemisation. The coupling can be conducted in aqueous buffer, no hazardous chemicals are necessary. Quite often side chain protection of the amino acids can be omitted, thus simplifying the synthetic procedure. Enzymatic peptide synthesis is a very good example of green chemistry… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.

References

Publications referenced by this paper.
Showing 1-4 of 4 references

Enzyme catalysed synthesis of benzoyl-arginyl-peptide esters

  • H. Eckstein, H.-J. Renner
  • Peptides
  • 1994

Papain-catalyzed peptide synthesis in organic solvent systems with extremely low water content

  • U. Fischer
  • Peptide Chemistry
  • 1987

Enzyme catalysed synthesis of benzoyl - arginyl - peptide esters “ , Peptides 1994 , Proceedings 23 th European Peptide Symposium , H . L . S . Maja Ed

  • H.-J. Renner Eckstein
  • Peptide Chemistry

Similar Papers

Loading similar papers…