Pdcd4 tumor suppressor: Properties, functions, and possible applications in oncology

Abstract

The inactivation of tumor suppressors and activation of protooncogenes are critical events in malignant cell transformation and tumor progression. Pdcd4 encodes a protein with tumor suppressor functions, which accounts for the increased interest in Pdcd4 as a potential diagnostic and prognostic marker and a target for anti-neoplastic therapy. The review… (More)
DOI: 10.3103/S0891416810020011

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