Pd-catalyzed enantioselective hydroalkoxylation of alkoxyallenes with phenol for construction of acyclic O,O-acetals.

@article{Jiang2015PdcatalyzedEH,
  title={Pd-catalyzed enantioselective hydroalkoxylation of alkoxyallenes with phenol for construction of acyclic O,O-acetals.},
  author={Liyin Jiang and Tao Jia and Min Wang and Jian Liao and Peng Cao},
  journal={Organic letters},
  year={2015},
  volume={17 5},
  pages={1070-3}
}
Palladium-catalyzed asymmetric intermolecular hydroalkoxylation of allenes has been developed by using phenol as a pronucleophile. Acyclic O,O-acetals were obtained in high yields (up to 98%) with good to excellent enantiomeric excesses (up to 94% ee).