Pd-catalyzed desulfitative arylation for the synthesis of 2,5-diarylated oxazole-4-carboxylates using dioxygen as the terminal oxidant.

@article{Tang2017PdcatalyzedDA,
  title={Pd-catalyzed desulfitative arylation for the synthesis of 2,5-diarylated oxazole-4-carboxylates using dioxygen as the terminal oxidant.},
  author={Xiaodong Tang and Kai Yang and Liying Zeng and Qiang Liu and Huoji Chen},
  journal={Organic & biomolecular chemistry},
  year={2017},
  volume={15 40},
  pages={8504-8507}
}
A desulfitative arylation of 2-aryloxazole-4-carboxylate with sodium arylsulfinates under an oxygen (O2) atmosphere to afford 2,5-diarylated oxazole-4-carboxylates is described. This transformation provides a novel approach for the utilization of sodium arylsulfinates as the aryl source and O2 as the sole oxidant.