PconsC: combination of direct information methods and alignments improves contact prediction

  title={PconsC: combination of direct information methods and alignments improves contact prediction},
  author={Marcin J. Skwark and Abbi Abdel-Rehim and Arne Elofsson},
  volume={29 14},
SUMMARY Recently, several new contact prediction methods have been published. They use (i) large sets of multiple aligned sequences and (ii) assume that correlations between columns in these alignments can be the results of indirect interaction. These methods are clearly superior to earlier methods when it comes to predicting contacts in proteins. Here, we demonstrate that combining predictions from two prediction methods, PSICOV and plmDCA, and two alignment methods, HHblits and jackhmmer at… CONTINUE READING
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