Pcdp1 is a central apparatus protein that binds Ca2+-calmodulin and regulates ciliary motility

@inproceedings{Dipetrillo2010Pcdp1IA,
  title={Pcdp1 is a central apparatus protein that binds Ca2+-calmodulin and regulates ciliary motility},
  author={Christen G Dipetrillo and Elizabeth F. Smith},
  booktitle={The Journal of cell biology},
  year={2010}
}
For all motile eukaryotic cilia and flagella, beating is regulated by changes in intraciliary calcium concentration. Although the mechanism for calcium regulation is not understood, numerous studies have shown that calmodulin (CaM) is a key axonemal calcium sensor. Using anti-CaM antibodies and Chlamydomonas reinhardtii axonemal extracts, we precipitated a… CONTINUE READING