PcToll3 was involved in anti-Vibrio response by regulating the expression of antimicrobial peptides in red swamp crayfish, Procambarus clarkii.

@article{Lan2016PcToll3WI,
  title={PcToll3 was involved in anti-Vibrio response by regulating the expression of antimicrobial peptides in red swamp crayfish, Procambarus clarkii.},
  author={Jiangfeng Lan and Shun Wei and Yu-qing Wang and Yun-Jia Dai and Jia-Gang Tu and Li-juan Zhao and Xin-Cang Li and Qi-Wei Qin and Nan Chen and Li Lin},
  journal={Fish & shellfish immunology},
  year={2016},
  volume={57},
  pages={17-24}
}
Tolls and Toll-like receptors (TLRs) play an important role in host immune defenses by regulating the expression of antimicrobial peptides (AMPs) and cytokines, but the functional differences of crustacean Tolls from Drosophila Tolls or Mammal TLRs are largely unknown. A novel Toll receptor, named PcToll3, was identified from red swamp crayfish, Procambarus clarkii. It was widely expressed in all detected tissues, and its transcript in hemocytes was up-regulated at 12 h after Vibrio… CONTINUE READING
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