Paxillin: a cytoskeletal target for tyrosine kinases.

  title={Paxillin: a cytoskeletal target for tyrosine kinases.},
  author={C. Heath Turner},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  volume={16 1},
  • C. Heath Turner
  • Published 1994 in
    BioEssays : news and reviews in molecular…
Paxillin is a recently identified member of the complex of cytoskeletal proteins that is found concentrated in cultured cells and in vivo at the cytoplasmic face of regions of cell attachment to the extracellular matrix. These sites, in view of their close proximity to the extracellular matrix, are well positioned to act as signal-transducing centers to 'report on' changes in the cells, immediate environment. Recent findings indicate that such signals are in part mediated through the activation… CONTINUE READING

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