Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium

@article{Jonker2004Pax9IR,
  title={Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium},
  author={L M H Jonker and Ralf Kist and A. Aw and Ilka Wappler and H. -U. Peters},
  journal={Mechanisms of Development},
  year={2004},
  volume={121},
  pages={1313-1322}
}
The epidermis is a derivative of the surface ectoderm. It forms a protective barrier and specific appendages including hair, nails, and different eccrine glands. The surface ectoderm also forms the epithelium of the oral cavity and tongue, which develop a slightly different barrier and form different appendages such as teeth, filiform papillae, taste papillae, and salivary glands. How this region-specific differentiation is genetically controlled is largely unknown. We show here that Pax9… CONTINUE READING

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