Pax7 Expressing Cells Contribute to Dermal Wound Repair, Regulating Scar Size through a β‐Catenin Mediated Process

@article{Amininik2011Pax7EC,
  title={Pax7 Expressing Cells Contribute to Dermal Wound Repair, Regulating Scar Size through a β‐Catenin Mediated Process},
  author={S. Amininik and Dylan Glancy and Corey Boimer and H. Whetstone and C. Keller and B. Alman},
  journal={STEM CELLS},
  year={2011},
  volume={29}
}
During skin wound healing, fibroblast‐like cells reconstitute the dermal compartment of the repaired skin filling the wound gap. A subset of these cells are transcriptionally active for β‐catenin/T‐cell factor (TCF) signaling during the proliferative phase of the repair process, and β‐catenin levels control the size of the scar that ultimately forms by regulating the number of dermal fibroblasts. Here, we performed cell lineage studies to reveal a source of the dermal cells in which β‐catenin… Expand
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