Pax genes: regulators of lineage specification and progenitor cell maintenance.

Abstract

Pax genes encode a family of transcription factors that orchestrate complex processes of lineage determination in the developing embryo. Their key role is to specify and maintain progenitor cells through use of complex molecular mechanisms such as alternate RNA splice forms and gene activation or inhibition in conjunction with protein co-factors. The… (More)
DOI: 10.1242/dev.091785

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Cite this paper

@article{Blake2014PaxGR, title={Pax genes: regulators of lineage specification and progenitor cell maintenance.}, author={Judith A. Blake and Melanie R. Ziman}, journal={Development}, year={2014}, volume={141 4}, pages={737-51} }