Paul Ehrlich's magic bullet concept: 100 years of progress

@article{Strebhardt2008PaulEM,
  title={Paul Ehrlich's magic bullet concept: 100 years of progress},
  author={Klaus Strebhardt and Axel Ullrich},
  journal={Nature Reviews Cancer},
  year={2008},
  volume={8},
  pages={473-480}
}
Exceptional advances in molecular biology and genetic research have expedited cancer drug development tremendously. The declared paradigm is the development of 'personalized and tailored drugs' that precisely target the specific molecular defects of a cancer patient. It is therefore appropriate to revisit the intellectual foundations of the development of such agents, as many have shown great clinical success. One hundred years ago, Paul Ehrlich, the founder of chemotherapy, received the Nobel… 

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