Patterns of selection on Plasmodium falciparum erythrocyte-binding antigens after the colonization of the New World.

@article{Yalcindag2014PatternsOS,
  title={Patterns of selection on Plasmodium falciparum erythrocyte-binding antigens after the colonization of the New World.},
  author={Erhan Yalcindag and Virginie Rougeron and Eric Elguero and C{\'e}line Arnathau and Patrick Durand and Sylvain Brisse and Laure Diancourt and Agn{\`e}s Aubouy and Pierre Becquart and Umberto D'Alessandro and Didier Fontenille and Dionicia Gamboa and Amanda Maestre and Didier M{\'e}nard and Lise Musset and Oscar O Noya and Vincent V{\'e}ron and Albina Wide and Bernard Carme and Eric Legrand and Christine Chevillon and Francisco J. Ayala and François N.R. Renaud and Franck Prugnolle},
  journal={Molecular ecology},
  year={2014},
  volume={23 8},
  pages={1979-93}
}
Pathogens, which have recently colonized a new host species or new populations of the same host, are interesting models for understanding how populations may evolve in response to novel environments. During its colonization of South America from Africa, Plasmodium falciparum, the main agent of malaria, has been exposed to new conditions in distinctive new human populations (Amerindian and populations of mixed origins) that likely exerted new selective pressures on the parasite's genome. Among… CONTINUE READING