Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma.

@article{Iwamoto2009PatternsOR,
  title={Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma.},
  author={Fabio M. Iwamoto and Lauren Eileen Abrey and Kathryn Beal and Phillip Gutin and Marc K. Rosenblum and Jonathan I. Epstein and Lisa M DeAngelis and Andrew B Lassman},
  journal={Neurology},
  year={2009},
  volume={73 15},
  pages={
          1200-6
        }
}
BACKGROUND Bevacizumab has recently been approved by the US Food and Drug Administration for recurrent glioblastoma (GBM). However, patterns of relapse, prognosis, and outcome of further therapy after bevacizumab failure have not been studied systematically. METHODS We identified patients at Memorial Sloan-Kettering Cancer Center with recurrent GBM who discontinued bevacizumab because of progressive disease. RESULTS There were 37 patients (26 men with a median age of 54 years). The most… CONTINUE READING
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