Patterns of proto-oncogene expression in human glioma cell lines.

  title={Patterns of proto-oncogene expression in human glioma cell lines.},
  author={Renato V Larocca and Michael I. Rosenblum and Bengt Westermark and Mark A. Israel},
  journal={Journal of neuroscience research},
  volume={24 1},
Previously reported studies have suggested that variations in the pattern of proto-oncogene expression within a specific tumor type may denote an underlying difference in the biology and clinical behavior of those tumors. To more sensitively characterize malignant tumors of the central nervous system, we have used Northern blot hybridization analysis to determine the patterns of expression of seven proto-oncogenes in 20 cell lines established from biopsy specimens of patients with malignant… CONTINUE READING


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