Patterns of protease production during prostate cancer progression: proteomic evidence for cascades in a transgenic model

@article{Bok2003PatternsOP,
  title={Patterns of protease production during prostate cancer progression: proteomic evidence for cascades in a transgenic model},
  author={Robert A. Bok and Elizabeth J Hansell and Tu Anh Pham Nguyen and Norman M. Greenberg and James H McKerrow and Marc A. Shuman},
  journal={Prostate Cancer and Prostatic Diseases},
  year={2003},
  volume={6},
  pages={272-280}
}
Extracellular proteases are recognized as critical factors in the progression of a number of carcinomas, including prostate cancer. Matrix metalloproteases (MMP) are important in processes of tumor growth, invasion and dissemination, but other classes of proteases, such as serine and cysteine proteases, also contribute. We utilized the TRAMP model for prostate cancer to elucidate proteases involved in prostate cancer progression. General proteomic analysis was performed on normal murine… CONTINUE READING

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Randomized double-blind pacebo-controlled trial of marimastat in patients with small cell lung cancer (SCLC) following response to first-line chemotherapy: an NCIC-CTG and EORTC study

  • FA Shepherd
  • Am Soc Clin Oncol
  • 2001

Correlation of the osteoblastic phenotype with prostatespecific antigen expression in metastatic prostate cancer : implications for paracrine growth

  • HG Rittenhouse, JA Finlay, SD Mikolajczyk, AW Partin
  • J Pathol
  • 1999

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