Patterns of population differentiation of candidate genes for cardiovascular disease

@article{Kullo2007PatternsOP,
  title={Patterns of population differentiation of candidate genes for cardiovascular disease},
  author={Iftikhar J. Kullo and Keyue Ding},
  journal={BMC Genetics},
  year={2007},
  volume={8},
  pages={48 - 48}
}
BACKGROUND The basis for ethnic differences in cardiovascular disease (CVD) susceptibility is not fully understood. We investigated patterns of population differentiation (FST) of a set of genes in etiologic pathways of CVD among 3 ethnic groups: Yoruba in Nigeria (YRI), Utah residents with European ancestry (CEU), and Han Chinese (CHB) + Japanese (JPT). We identified 37 pathways implicated in CVD based on the PANTHER classification and 416 genes in these pathways were further studied; these… CONTINUE READING

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