Patterns of lymphadenopathy in thoracic malignancies.

@article{Sharma2004PatternsOL,
  title={Patterns of lymphadenopathy in thoracic malignancies.},
  author={Amita Sharma and Panos Fidias and L. A. Hayman and Susanne L Loomis and Katherine H. Taber and Suzanne L. Aquino},
  journal={Radiographics : a review publication of the Radiological Society of North America, Inc},
  year={2004},
  volume={24 2},
  pages={
          419-34
        }
}
  • Amita Sharma, P. Fidias, S. Aquino
  • Published 1 March 2004
  • Medicine
  • Radiographics : a review publication of the Radiological Society of North America, Inc
There are different lymphatic drainage pathways in the thorax that are relevant in the staging of lung cancer, breast cancer, lymphoma, esophageal cancer, and malignant mesothelioma. To properly search for metastatic spread, it is important to carefully evaluate the specific nodal stations that drain the thoracic structures from which a primary tumor originates. Because size criteria have limitations in the prediction of nodal status, pathologic confirmation is essential for accurate staging… 

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References

SHOWING 1-10 OF 49 REFERENCES

Bronchogenic carcinoma: analysis of staging in the mediastinum with CT by correlative lymph node mapping and sampling.

TLDR
The relative insensitivity of CT makes formal nodal sampling at the time of mediastinoscopy or thoracotomy essential to detect lymph node metastases.

Preoperative staging of non-small-cell lung cancer with positron-emission tomography.

TLDR
The use of PET to identify the stage of the disease resulted in a different stage from the one determined by standard methods in 62 patients: the stage was lowered in 20 and raised in 42.

Thin section computed tomography in the prone position for detection of axillary lymph node metastases in breast cancer.

TLDR
TS-CT is an accurate predictor of axillary lymph node involvement, however, the upper limit of accuracy was approximately 85% for the imaging diagnoses, mainly because of the existance of micrometastases.

Noninvasive staging of non-small cell lung cancer: a review of the current evidence.

TLDR
PET scanning is more accurate than CT scanning or EUS for detecting mediastinal metastases and the NPVs of the clinical evaluations for brain, abdominal, and bone metastases are > or = 90%, suggesting that routinely imaging asymptomatic lung cancer patients may not be necessary.

CT-pathologic correlation of axillary lymph nodes in breast carcinoma.

TLDR
Although superior to physical examination, CT was not an accurate predictor of axillary LN involvement, primarily because of its low negative predictive value.

Hodgkin disease: contributions of chest CT in the initial staging evaluation.

TLDR
Routine chest CT examinations are valuable in the clinical management of those patients for whom radiation therapy is planned, and are concluded that routine chest radiographs and chest computed tomography scans are valuable.

MR study of N2 disease in lung cancer: contrast-enhanced method using gadolinium-DTPA.

Evaluation of axillary status in breast cancer. CT-based determination of sentinel lymph node size.

TLDR
The CT criteria were highly accurate for identification and diagnostic assessment of SLN and useful for evaluating the axillary status in patients with breast cancer.