Patterns of initial and intracranial failure in metastatic EGFR-mutant non-small cell lung cancer treated with erlotinib.

@article{Patel2017PatternsOI,
  title={Patterns of initial and intracranial failure in metastatic EGFR-mutant non-small cell lung cancer treated with erlotinib.},
  author={Suchit Patel and Andreas Rimner and Amanda L Foster and Zhigang Zhang and K M Woo and Helena A. Yu and Gregory J Riely and Abraham Jing-Ching Wu},
  journal={Lung cancer},
  year={2017},
  volume={108},
  pages={109-114}
}
OBJECTIVES Patients with metastatic EGFR-mutant (mEGFRmt) NSCLC have favorable survival when treated with erlotinib. We hypothesized that treatment failure in most patients is limited to initial sites of disease, in which case incorporating local therapy such as radiation might further delay progression. We therefore analyzed patterns and predictors of… CONTINUE READING