Patterns of inheritance of the symptoms of Huntington's disease suggestive of an effect of genomic imprinting.

@article{Ridley1991PatternsOI,
  title={Patterns of inheritance of the symptoms of Huntington's disease suggestive of an effect of genomic imprinting.},
  author={Rosalind M. Ridley and Chris D Frith and Lindsay A. Farrer and P. Michael Conneally},
  journal={Journal of medical genetics},
  year={1991},
  volume={28 4},
  pages={224-31}
}
The interaction of symptomatology (rigidity/chorea) in Huntington's disease (HD) with age of onset (AO) was examined using data from the Research Roster for Huntington's Disease Patients and Families. It was shown that AO varies between families and between paternal and maternal transmission and that rigidity is associated specifically with very early onset… CONTINUE READING