Patterns of genomic imbalances in human solid tumors (Review).

  title={Patterns of genomic imbalances in human solid tumors (Review).},
  author={Erich Gebhart and Thomas Liehr},
  journal={International journal of oncology},
  volume={16 2},
Based on comparative studies on CGH-detected genomic imbalances in head and neck squamous cell carcinomas and in ovarian tumors it was supposed that the patterns of genomic imbalances in human tumors are not only related to the oncogenic progress and tumor progression or specific for the tissue of origin, but also could be influenced by environmental (mutagenic) factors present in the environment of the evolving cancer. To base this hypothesis on a more solid ground, data obtained by use of… CONTINUE READING


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