Patterns of failure after concurrent bevacizumab and hypofractionated stereotactic radiation therapy for recurrent high-grade glioma.

@article{Shapiro2013PatternsOF,
  title={Patterns of failure after concurrent bevacizumab and hypofractionated stereotactic radiation therapy for recurrent high-grade glioma.},
  author={Lauren Q. Shapiro and Kathryn F. Beal and Anuj Goenka and S Karimi and Fabio M. Iwamoto and Y Yamada and Zhigang Zhang and Andrew B. Lassman and Lauren E. Abrey and Philip H. Gutin},
  journal={International journal of radiation oncology, biology, physics},
  year={2013},
  volume={85 3},
  pages={
          636-42
        }
}
PURPOSE Concurrent bevacizumab with hypofractionated stereotactic radiation therapy (HSRT) is safe and effective for the treatment of recurrent high-grade gliomas (HGG). The objective of this study was to characterize the patterns of failure after this treatment regimen. METHODS AND MATERIALS Twenty-four patients with recurrent enhancing HGG were previously treated on an institutional review board-approved protocol of concurrent bevacizumab and reirradiation. Patients received 30 Gy in 5… CONTINUE READING

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