Patterns of evolution of host proteins involved in retroviral pathogenesis

@article{Ortiz2005PatternsOE,
  title={Patterns of evolution of host proteins involved in retroviral pathogenesis},
  author={Mill{\'a}n Ortiz and Gabriela Bleiber and Raquel De la Varga Mart{\'i}nez and Henrik Kaessmann and Amalio Telenti},
  journal={Retrovirology},
  year={2005},
  volume={3},
  pages={11 - 11}
}
Evolutionary analysis may serve as a useful approach to identify and characterize host defense and viral proteins involved in genetic conflicts. We analyzed patterns of coding sequence evolution of genes with known (TRIM5α and APOBEC3G) or suspected (TRIM19/PML) roles in virus restriction, or in viral pathogenesis (PPIA, encoding Cyclophilin A), in the same… CONTINUE READING