Patterns of evolution of MHC class II genes of crows (Corvus) suggest trans-species polymorphism

@inproceedings{Eimes2015PatternsOE,
  title={Patterns of evolution of MHC class II genes of crows (Corvus) suggest trans-species polymorphism},
  author={John A Eimes and Andrea K. Townsend and Irem Sepil and Isao Nishiumi and Yoko Satta},
  booktitle={PeerJ},
  year={2015}
}
A distinguishing characteristic of genes that code for the major histocompatibility complex (MHC) is that alleles often share more similarity between, rather than within species. There are two likely mechanisms that can explain this pattern: convergent evolution and trans-species polymorphism (TSP), in which ancient allelic lineages are maintained by balancing selection and retained by descendant species. Distinguishing between these two mechanisms has major implications in how we view… CONTINUE READING