Histopathologic analysis of endometrial biopsies in TUTH, Nigeria, a 5 year critical review, Niger
- AM Dauda
- J Med
Conditions affecting the endometrium can be classified as benign or malignant. Benign endometrial histology includes atrophy, proliferative endometrium, secretory endometrium, disordered or dyssynchronous endometrium, and endometritis. Endometrial biopsy samples taken by gynecologists are among the most frequent daily activities. This study was done to evaluate histopathology of endometrium for identifying the endometrial causes of complaints among women for whom endometrial biopsy was done. A five year retrospective descriptive study was conducted in Tikur Anbessa Specialized Teaching Hospital (TASTH) from April 2008 to May 2013 involving 448 patient records. The data was collected using Structured, self-prepared questionnaires. All women who had undergone endometrial biopsy were collected from pathologic unit of the hospital and the card of patients retrieved from the registrar. SPSS version 20.0 was used for data entry and analysis and logistic regression was used to identify the predictor variables. The mean and median age of the study patients were 36.75 + 10.41 and 35, respectively and 62.5% of the study participants were multi-parous. The commonest AUB was Metromenorrhagia. The commonest pattern in these patients was normal cycling endometrium (44.9%). Endometrial polyp (15.2%), complications of pregnancy (9.2%), atrophic endometrium (5.8%) and TB endometritis (4.5%) were in the abnormal findings. Risk of pregnancy complications and Tuberculosis were found to be higher in those women aged 35 or younger. Atrophic endometrium and polyp were significantly associated with in patients with age of above thirty five. Abnormal endometrial histopathological findings were found to be high. Endometrial polyp, atrophic endometrium and hyperplasia were significantly associated with women above the age of 35. We recommend for more and further prospective studies on pathologies involving the endometrium and our history taking and physical examination need to be focused.