Patterns of cerebral amyloid angiopathy define histopathological phenotypes in Alzheimer's disease.

@article{Allen2014PatternsOC,
  title={Patterns of cerebral amyloid angiopathy define histopathological phenotypes in Alzheimer's disease.},
  author={Nancy C. Allen and Andrew C. Robinson and Julie Snowden and Yvonne S. Davidson and David M. A. Mann},
  journal={Neuropathology and applied neurobiology},
  year={2014},
  volume={40 2},
  pages={
          136-48
        }
}
AIMS Pathological heterogeneity of Aβ deposition in senile plaques (SP) and cerebral amyloid angiopathy (CAA) in Alzheimer's disease (AD) has been long noted. The aim of this study was to classify cases of AD according to their pattern of Aβ deposition, and to seek factors which might predict, or predispose towards, this heterogeneity. METHODS The form, distribution and severity of Aβ deposition (as SP and/or CAA) was assessed semiquantitatively in immunostained sections of frontal, temporal… CONTINUE READING

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