Patterns of Immune Infiltration in Breast Cancer and Their Clinical Implications: A Gene-Expression-Based Retrospective Study

@inproceedings{Ali2016PatternsOI,
  title={Patterns of Immune Infiltration in Breast Cancer and Their Clinical Implications: A Gene-Expression-Based Retrospective Study},
  author={Hamid Raza Ali and Leon Chlon and Paul D P Pharoah and Florian Markowetz and Carlos Caldas},
  booktitle={PLoS medicine},
  year={2016}
}
BACKGROUND Immune infiltration of breast tumours is associated with clinical outcome. However, past work has not accounted for the diversity of functionally distinct cell types that make up the immune response. The aim of this study was to determine whether differences in the cellular composition of the immune infiltrate in breast tumours influence survival and treatment response, and whether these effects differ by molecular subtype. METHODS AND FINDINGS We applied an established… CONTINUE READING
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