Patterns of Historical Balancing Selection on the Salmonid Major Histocompatibility Complex Class II β Gene

@article{Aguilar2006PatternsOH,
  title={Patterns of Historical Balancing Selection on the Salmonid Major Histocompatibility Complex Class II β Gene},
  author={Andres Aguilar and John Carlos Garza},
  journal={Journal of Molecular Evolution},
  year={2006},
  volume={65},
  pages={34-43}
}
Allelic variation in the major histocompatibility class (MHC) IIB gene of salmonids is analyzed for patterns indicative of natural selection acting at the molecular level. Sequence data for the second exon of this MHC gene were generated for 11 species in three salmonid genera: Oncorhynchus, Salmo, and Salvelinus. Phylogenetic analysis of nucleotide sequences revealed: (1) monophyletic grouping of alleles from each genus, (2) transspecies evolution of alleles within Salmo and Salvelinus, and (3… CONTINUE READING

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