Patterns and variability of tumor oxygenation in human soft tissue sarcomas, cervical carcinomas, and lymph node metastases.

@article{Brizel1995PatternsAV,
  title={Patterns and variability of tumor oxygenation in human soft tissue sarcomas, cervical carcinomas, and lymph node metastases.},
  author={David M. Brizel and Gary L. Rosner and Leonard R Prosnitz and Mark W. Dewhirst},
  journal={International journal of radiation oncology, biology, physics},
  year={1995},
  volume={32 4},
  pages={1121-5}
}
PURPOSE The validity of tumor pO2 measurement as a predictive outcome assay depends upon demonstrating that intrapatient pO2 variation is less than interpatient variation. No consensus exists regarding the appropriate distance between individual measurements. This distance could affect the calculation of the hypoxic fraction (% pO2s < 5 mm Hg) and the assessment of intra/interpatient heterogeneity. This study was performed to evaluate tumor oxygenation and to assess the effects of two different… CONTINUE READING

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