Patterns and predictors of the use of different antiretroviral drug regimens at treatment initiation in the UK.

@article{Easterbrook2008PatternsAP,
  title={Patterns and predictors of the use of different antiretroviral drug regimens at treatment initiation in the UK.},
  author={Philippa Jane Easterbrook and Andrew N Phillips and Teresa A. Garrett Hill and Ryanne Matthias and Martin Fisher and Brian Gazzard and Richard Gilson and George Scullard and Margaret A T Johnson and David T Dunn and Chloe M. Orkin and Jane K Anderson and Achim Schwenk and Clifford S Leen and Caroline Sabin},
  journal={HIV medicine},
  year={2008},
  volume={9 1},
  pages={47-56}
}
BACKGROUND We describe the patterns of antiretroviral drug use at treatment initiation from 1996 to 2005 in a large UK multicentre cohort. METHODS We examined trends over time and across 10 clinical sites in stage of disease and type of antiretroviral therapy (ART). Multivariable regression was used to identify factors associated with the CD4 cell count at ART initiation, and with the choice of a protease inhibitor (PI) over a nonnucleoside reverse transcriptase inhibitor (NNRTI), and use of… CONTINUE READING