Patterned glass surfaces direct cell adhesion and process outgrowth of primary neurons of the central nervous system.

@article{Saneinejad1998PatternedGS,
  title={Patterned glass surfaces direct cell adhesion and process outgrowth of primary neurons of the central nervous system.},
  author={Sheyda Saneinejad and Molly S Shoichet},
  journal={Journal of biomedical materials research},
  year={1998},
  volume={42 1},
  pages={
          13-9
        }
}
Glass surfaces were patterned with cell-adhesive regions of laminin adhesive peptides YIGSR, RGD, and IKVAV, and cell-repulsive regions of poly(ethylene glycol) (PEG). The patterns were created by sputter-coating titanium and then gold onto glass coverslips through electron microscope grids. Gold surfaces were modified with cysteine-terminated peptides to have approximately 450 fmol/ cm2 of peptide incorporated on the glass coverslips as determined with radiolabeled CGYIGSR. Amine… CONTINUE READING
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