Patterned expression of BDNF and NT-3 in the retina and anterior segment of the developing mammalian eye.


PURPOSE The neurotrophins brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) are hypothesized to play an important role in vertebrate eye development because of their patterned expression in the developing and adult neuroretina, their regulated response to retinal and optic nerve injury, and the effects of altered neurotrophin signaling on… (More)

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