Pattern separation deficits following damage to the hippocampus.

  title={Pattern separation deficits following damage to the hippocampus.},
  author={C Brock Kirwan and Andrew Hartshorn and Shauna M. Stark and Naomi J Goodrich-Hunsaker and R. O. Hopkins and Craig E. L. Stark},
  volume={50 10},
Computational models of hippocampal function propose that the hippocampus is capable of rapidly storing distinct representations through a process known as pattern separation. This prediction is supported by electrophysiological data from rodents and neuroimaging data from humans. Here, we test the prediction that damage to the hippocampus would result in pattern separation deficits by having memory-impaired patients with bilateral hippocampal damage study a series of objects or faces and then… CONTINUE READING