Pattern recognition receptors in companion and farm animals - the key to unlocking the door to animal disease?

@article{Werling2007PatternRR,
  title={Pattern recognition receptors in companion and farm animals - the key to unlocking the door to animal disease?},
  author={Dirk Werling and Tracey J. Coffey},
  journal={Veterinary journal},
  year={2007},
  volume={174 2},
  pages={240-51}
}
The innate immune system is essential for host defence and is responsible for early detection of potentially pathogenic microorganisms. Upon recognition of microbes by innate immune cells, such as macrophages and dendritic cells, diverse signalling pathways are activated that combine to define inflammatory responses that direct sterilisation of the threat and/or orchestrate development of the adaptive immune response. Innate immune signalling must be carefully controlled and regulation comes in… CONTINUE READING
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