Pattern recognition receptor function in neutrophils.

  title={Pattern recognition receptor function in neutrophils.},
  author={Christina J Thomas and Kate Schroder},
  journal={Trends in immunology},
  volume={34 7},
Previously, neutrophils were largely ignored in the pattern recognition receptor (PRR) signaling field. However, interest in neutrophil biology has been revitalized by emerging roles for neutrophils in promoting protective and pathogenic T helper (Th)17-driven immune responses and in orchestrating innate and adaptive immunity via cytokine/chemokine production. Although it was originally assumed that neutrophils are transcriptionally inert and their short lifespan limits their ability to respond… CONTINUE READING
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